Sarcoma is a type of cancer that starts in soft tissues or the bones of the body, including fat, cartilage, muscle, blood vessels, fibrous tissue, or supportive or connective tissue. Different types of sarcomas are based on where the tumor forms. DNA changes in soft tissue sarcoma are common. But they're usually developed during life rather than having been inherited earlier in birth. Acquired mutations may result from cancer-causing cells or heavy radiation exposure. In most sarcomas, they happen for no actual reason. The total 5yr survival rate for sarcoma is 65%. About 60% of sarcomas are found as localized sarcoma. The 5-year survival rate for people with localized sarcoma is 81%. About 19% of sarcomas are found in a locally unconventional stage